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July 29, 2026

The 10 Most Commonly Used Drugs by Teenagers

Alcohol: More than half of high school seniors admit to abusing alcohol...

  • Alcohol: More than half high school seniors admit to abusing alcohol. Alcohol is the most frequently used and abused substance.
  • Marijuana: The second most used substance by teens. The use of marijuana use has been on a steady increase. Part of the appeal is the notion that it is not harmful
  • Nicotine: The use of cigarettes has declined, however there is a rising trend in the use of e-cigarettes/vaping, due to the lack of regulation
  • Adderall: This medication is prescribed primarily for ADD/ADHD. The medication will speed up the functioning of the body. Other prescription names
    • Dexedrine
    • Ritalin
    • Concerta
    • Vyvanse
  • OxyContin (Opioid): Opioids are powerful, dangerous, and highly addictive. This class of drugs is used for pain. Other prescription names
  • Tranquilizers: These substances slow the central nervous system. This class of drugs is dangerous and highly addictive. Other prescription names
    • Benzodiazepines: Ativan – Xanax – Klonopin – Valium
    • Barbiturates: Phenobarbital – Butalbital
    • Sleep Medications: Ambien – Lunesta - Sonata
  • Spice/K-2: This a synthetic marijuana, the chemicals used to make this are dangerous and can cause dramatic unexpected results
  • Hallucinogens: This group of substance s contains psychoactive drugs that distort realty by triggering hallucinations, delusional thinking and skewed experiences. These substances include:
    • LSD
    • Peyote
    • Mescaline
    • Mushrooms
  • Inhalants: These substances are abused by sniffing, snorting, or huffing fumes. The results of this drug is short lasting and quite dangerous.                         The substance include:
    • Gasoline
    • Glue
    • Nail Polish Remover
    • Paint
    • Hair Spray
    • Computer Duster
    • Whipped Cream aerosols
  • Dextromethorphan (DXM): Many over the counter cough and cold medicines contain this active ingredient. When abused it can produce intoxicating and dissociative effect.

Reference: ProjectKnow.com

About the Author

Dr. Robert Watkins III
Dr. Watkins has been practicing Psychiatric Medicine for over 14 years. He completed his Adult Psychiatry training at Columbia University as well as a Child and Adolescent fellowship at the University of Texas. Dr. Watkins works closely with his team to provide the safest and best care possible to kids served. He pushes his team towards excellence and is committed to improving wellness and quality of life.‍

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